Blood cell analysis under hypoxia. Precise gas control throughout microfluidic system.
About
RBC sickling/unsickling
RBC sickling and unsickling is dynamically monitored in real time under flow.
Hypoxic cell adhesion
Integrated with Adhesion BioChip and Endothelium-on-a-chip.
Hypoxic microvascular occlusion
Integrated with OcclusionChip.
Hypoxic whole blood rheology
Integrated with RheologyChip
TypicalUses
Personalized Medicine, Research, Drug Development
Targeted Therapies
Efficacy of emerging targeted therapies in SCD can be assessed under hypoxia.
Curative Therapies
NHLBI-supported multi-site study to assess RBC mediated microcapillary occlusions before and after a gene-based therapy for curative intent.